Rimantadine Hydrochloride CAS 1501-84-4
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Molecular Formula: C12H21N·HCL
Molecular Weight: 215.77
CAS No.: 1501-84-4
It is an antiviral drug, acts early in the viral replication cycle by inhibiting the shelling of virus particles in host cells. It is used to prevent the infection caused by influenza A virus strain.
Description
White crystalline powder. Soluble in ethanol, chloroform or water.
Application
Intermediate for synthesis of antiviral drugs.
Packing and Storage
Preserve in well-closed containers, and store between 15°C to 30°C.
Minimum Order
One package
| Title | Content |
|---|---|
| Introduction | Rimantadine Hydrochloride is an antiviral medication used primarily for the treatment and prevention of influenza A virus infections. It is available under the brand name Flumadine. |
| Mechanism of Action | Rimantadine inhibits the M2 protein of the influenza A virus, blocking the hydrogen ion channel activity and preventing viral entry and replication. |
| Medical Uses | – Treatment of Influenza A: Effective when taken within 48 hours of symptom onset.<br>- Prevention of Influenza A: Used during flu outbreaks to prevent infection. |
| Dosage Forms | – Oral Tablets: 100 mg tablets.<br>- Oral Suspension: Prepared from tablets for lower dosages or patients who cannot swallow tablets. |
| Dosage | – Adults: 100 mg twice daily for 7 days (treatment) or 100 mg twice daily (prevention).<br>- Children: 1-9 years: 5 mg/kg (up to 150 mg) once daily; ≥10 years: 100 mg twice daily.<br>- Elderly: 100 mg daily. |
| Common Side Effects | – Gastrointestinal: Nausea, vomiting, diarrhea, loss of appetite.<br>- Neurological: Insomnia, dizziness, headache, anxiety.<br>- Other: Dry mouth, fatigue. |
| Serious Side Effects | – Allergic Reactions: Rash, swelling, difficulty breathing.<br>- Neurological: Seizures, severe dizziness. |
| Precautions | – Special Populations: Use with caution in patients with liver or kidney impairment.<br>- Pregnancy and Breastfeeding: Use only if clearly needed; consult a doctor.<br>- Elderly: More susceptible to side effects. |
| Storage Conditions | Store at room temperature (20°C to 25°C), keep dry and cool. |
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