(R)-(+)-4-Isopropyl-2-oxazolidinone
Pharmaceutical Materials 2025-03-02
CAS Number: 95530-58-8
Molecular Formula: C6H11NO2
Molecular Weight: 129.16 g/mol
Melting Point: 70-73°C
Appearance: White crystalline powder
Solubility: Soluble in water, slightly soluble in alcohol
Usage: Used as a chiral organic synthesis intermediate and pharmaceutical chemical raw material.
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| Attribute | Details |
|---|---|
| Name | (R)-(+)-4-Isopropyl-2-oxazolidinone |
| CAS Number | 95530-58-8 |
| Synonyms | (4R)-(+)-4-Isopropyl-2-oxazolidinone; R-Isopropyl-2-oxazolidinone; (R)-4-Isopropyl-2-oxazolidinone |
| Molecular Formula | C6H11NO2 |
| Molecular Weight | 129.16 g/mol |
| Appearance | White to light yellow crystalline powder |
| Melting Point | 70-73°C |
| Boiling Point | 291.1°C at 760 mmHg |
| Density | 1.038 g/cm³ |
| Flash Point | 129.9°C |
| Solubility | Soluble in water and certain organic solvents |
| Chemical Properties | Chiral oxazolidinone compound; contains an amide unit that can undergo condensation reactions with acyl chlorides under alkaline conditions to form corresponding amide derivatives |
| Applications | Used as a chiral organic synthesis intermediate and a basic raw material in pharmaceutical chemistry; for example, it can be used in the synthesis of biologically active molecules such as pemetrexed. It also serves as an organic catalyst in organic synthesis. |
| Safety Information | Irritating to eyes, respiratory system, and skin; avoid contact with skin and eyes; wear suitable protective clothing; in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
