(R)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione 2-hydroxybenzoate

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Category:Other Pharmaceutical   MOQ:100KG  Shipped directly from China

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Introduction

Intermediate 7 of Alagoli is an organic compound. It is usually a white solid with strong biological activity.

Attention should be paid to safety when using intermediate 7 of Alagoli, laboratory operating procedures should be followed, appropriate protective equipment should be worn, and skin contact and inhalation of its vapors should be avoided. The compound should be stored properly and avoid contact with oxygen, sunlight, high temperatures, or sources of fire to prevent accidents.

Name 1821300-84-8
Synonyms 1821300-84-8
CAS 1821300-84-8
Molecular Formula C35H30F5N3O6
Molar Mass 683.63

Fundamental Chemical Properties

Property Specification
Chemical Name (R)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2.4(1H,3H)-dione 2-hydroxybenzoate
CAS No. 1821300-84-8
Molecular Formula C₃₅H₃₀F₄N₄O₆
Molecular Weight 678.63 g/mol
Appearance White to off-white crystalline powder
Melting Point 180-185°C (dec.)
Solubility DMSO: ≥50 mg/mL; Water: <0.1 mg/mL

Key Functional Properties & Applications

Function Application
Pharmaceutical Intermediate Kinase inhibitor development
Chiral Building Block Asymmetric synthesis
Biological Modulator Preclinical research
Salt Form Improved stability vs. free base
Targeted Therapy Agent Oncology candidate compounds

Safety & Handling Guidelines

Parameter Requirement
Storage Conditions -20°C, under inert atmosphere
Light Sensitivity Protect from light
Skin Contact Use nitrile gloves
Respiratory Protection Use fume hood if airborne
Disposal Pharmaceutical waste protocol

Key Features:

High stereochemical purity (>99% enantiomeric excess)

Enhanced bioavailability via salt formation

Multi-target potential due to complex pharmacophore

Thermal stability up to 150°C in solid state

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