Quinine HCl
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80071760
CAS NO.130-89-2
Purity 95%
MDL NumberMFCD00078498
EINEC205-003-2
Molecular Formula C20H24N2O2.HCl
Molecular Weight 360.883
Melting point: 174~178℃
| Item | Information |
|---|---|
| Mechanism of Action | Quinine hydrochloride is an alkaloid with antimalarial properties. Its exact mechanism of action against malaria parasites is not fully understood, but it is believed to interfere with the parasite’s ability to metabolize hemoglobin. |
| Indications | – Used as an antimalarial drug for treating malaria infections.<br>- Used as a bittering agent in beverages, such as tonic water.<br>- Used in the treatment of nocturnal leg cramps and some muscular disorders. |
| Dosage Forms | – Available as tablets, injections, and in solution form. |
| Common Side Effects | – Cinchonism (headache, nausea, vomiting, tinnitus, hearing loss, blurred vision).<br>- Hypoglycemia, especially in pregnant women.<br>- Gastrointestinal disturbances, dizziness, and allergic reactions. |
| Serious Side Effects | – Cardiac arrhythmias, hypotension, and thrombocytopenia.<br>- Severe allergic reactions, including anaphylaxis.<br>- In rare cases, acute hemolytic reactions (blackwater fever) in patients with G6PD deficiency. |
| Drug Interactions | – May interact with other medications, including anticoagulants, antidiabetic drugs, and certain antibiotics. |
| Special Precautions | – Use with caution in patients with cardiac conditions, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and during pregnancy.<br>- Avoid rapid intravenous administration to prevent hypotension. |
| Storage Conditions | Store in a cool, dry place, protected from light. |
| Additional Information | – Quinine hydrochloride is derived from the bark of the cinchona tree.<br>- It is also used in research for its effects on potassium channels. |
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