Quinestrol CAS NO.152-43-2
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017321
CAS NO.152-43-2
Purity 97%
MDL NumberMFCD00079189
Molecular Formula C25H32O2
Molecular Weight 364.5204
| Aspect | Details |
|---|---|
| Chemical Properties | – Molecular Formula: C25H32O2<br>- Molecular Weight: 364.5 g/mol<br>- CAS Number: 152-43-2 |
| Mechanism of Action | Quinestrol is a synthetic estrogen that acts by binding to estrogen receptors in target cells. It regulates gene transcription, leading to the formation of specific proteins that express the effects of estrogen. It also increases the synthesis of sex hormone-binding globulin (SHBG) and suppresses follicle-stimulating hormone (FSH) secretion. |
| Indications | – Used in hormone replacement therapy to treat symptoms of menopause, such as hot flashes.<br>- Used to treat breast and prostate cancer. |
| Pharmacokinetics | – Absorption: Absorbed following oral administration.<br>- Distribution: Stored in adipose tissue and slowly released.<br>- Metabolism: Metabolized principally to the parent compound, ethinyl estradiol.<br>- Excretion: Metabolites are excreted primarily via urine. |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture. |
| Special Considerations | – Use with caution in patients with a history of thromboembolic disorders, liver disease, or unexplained vaginal bleeding.<br>- Regular monitoring of liver function and blood pressure is recommended. |
| Adverse Effects | – Common: Nausea, headache, breast tenderness.<br>- Serious: Thromboembolic events, liver toxicity |
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