Quercetin
Pharmaceutical Materials 2025-03-02
CAS Number: 117-39-5
Molecular Formula: C15H10O7
Molecular Weight: 302.24 g/mol
Appearance: Yellow needle-like crystals (dihydrate)
Usage: Widely used in dietary supplements for its antioxidant and anti-inflammatory properties.
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| Category | Details |
|---|---|
| Chemical Name | Quercetin |
| CAS Number | 117-39-5 |
| Other Names | Quercetrin, Sophoretin |
| Molecular Formula | C15H10O7 |
| Molecular Weight | 302.24 g/mol |
| Appearance | Yellow crystalline powder |
| Melting Point | 314-317°C (decomposes) |
| Solubility | Soluble in dimethyl sulfoxide (DMSO), ethanol, and methanol; insoluble in water |
| Classification | Flavonoid (subclass: flavonol) |
| Natural Sources | Abundant in fruits and vegetables, especially red onions, apples, berries, and green tea |
| Pharmacological Actions | – Antioxidant – Anti-inflammatory – Antitumor – Anti-proliferative – Pro-apoptotic – Anti-metastatic – Blood pressure-lowering – Blood lipid-lowering |
| Mechanism of Action | – Inhibits the expression of survivin protein, maintaining the cell cycle at the G0/G1 stage – Upregulates the expression of miR-145. activating caspase-8. caspase-9. and caspase-3 – Decreases the expression of anti-apoptotic proteins (Bcl-2. Bcl-xl) and increases the expression of pro-apoptotic proteins (Bax, Bad) |
| Applications | Used in dietary supplements, cosmetics, and pharmaceuticals due to its various health benefits |
| Safety | Generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA); however, consult a healthcare professional before use, especially if pregnant or breastfeeding |
| Storage Conditions | Store in a cool, dry place, away from direct sunlight and moisture |
