Pyridoxine Hydrochloride (Vitamin B6) CAS 58-56-0

Pyridoxine hydrochloride (Vitamin B6) is a white or almost white crystalline powder, odorless, sour and bitter, and sublimated by heating. The dried product is stable to air and light, and the aque...

Category:Vitamins

Introduction

Pyridoxine hydrochloride (Vitamin B6) is a white or almost white crystalline powder, odorless, sour and bitter, and sublimated by heating. The dried product is stable to air and light, and the aqueous solution is gradually oxidized and changed color when exposed to air, and the oxidation accelerates with the increase of pH value. Mp205-209°C (decomposition), with maximum absorption (0.1mol/LHCl) at a wavelength of 290nm±1nm. Easily soluble in water (1:4.5), the solution is acidic, slightly soluble in ethanol (1:90) and acetone, but insoluble in ether and chloroform.

Application

Pyridoxine hydrochloride (Vitamin B6), chemical name 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine hydrochloride, exists in rice bran, vegetables, yeast, molasses, fat and so on. It can be synthesized from methyl methoxyacetate, acetone and ethyl cyanoacetate. Pyridoxine hydrochloride is a vitamin drug, which can treat all kinds of diseases caused by lack of VB6 clinically. Pyridoxine hydrochloride is used for vomiting during pregnancy, radiation sickness, etc Isoniazid poisoning and the prevention and treatment of gastrointestinal reactions of antineoplastic drugs are sometimes used as adjuvant treatment for pellagra and other kinds of malnutrition. Pyridoxine hydrochloride is also used as feed additive, food additive and ultraviolet absorbent in cosmetics.

Specification

Pharmacopoeia BP2015/USP38
Appearance A white or almost white crystalline powder
Appearance   of solution Clear, not more intense than Y7
Identification (1)      Should   be positive reaction

(2)      Consistent   with the reference IR spectra

pH 2.4~3.0
Heavy   metals NMT20ppm
Loss   on drying NMT0.5%
Sulfated   ash NMT0.1%
Chloride   content 16.9~17.6%
Related   substances:
Impurity B NMT0.15%
Unspecified impurities NMT0.10%
Total impurities NMT0.2%
Residual   solvent (Ethanol) NMT0.3%
Assay 99.0% ~ 101.0%

Packing

25kgs / drum

Storage

Be kept airtight, dry and in cool place.

Shelf Life :

36 months from date of production when stored in good condition.

Minimum Order

100kgs

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