Pharmaceutical Materials

CAS No.628-13-7

Name:

Pyridine Hydrochloride

Synonyms:

PYRIDINE HCL

Pyridinium chloride

PYRIDINIUM CHLORIDE

Pyridine Hydrochloride

PYRIDINE HYDROCHLORIDE

PYRIDINIUM MONOCHLORIDE

PYRIDINE HYDROCHLORIDE PYRIDINE HYDROCHLORIDE

Reference Information:

Introduction    pyridine, an organic compound, is a six-membered heterocyclic compound containing a nitrogen heteroatom. Can be seen as one of the benzene molecules (CH) substituted by N compounds, so also known as nitrogen benzene, colorless or yellowish liquid, there is a smell. Pyridine and its homologs are found in bone tar, coal tar, gas, shale oil, and petroleum. Pyridine in the industry can be used as denaturants, dyeing AIDS, and synthesis of a series of products (including drugs, disinfectants, dyes, etc.) of raw materials. Pyridine hydrochloride is the hydrochloride state of pyridine.

Application    pyridine hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, can be used in laboratory research and development process and chemical pharmaceutical production process, it is also one of the raw materials for the production of methyl erythromycin.

preparation method    dry hydrochloric acid gas can be introduced into pyridine for direct salt formation. Specific Method: reaction bottle containing 100g of sodium chloride, concentrated hydrochloric acid 200 ml under stirring, Dropwise and concentrated sulfuric acid to produce hydrochloric acid gas, after drying by concentrated sulfuric acid, into the ice water bath cooling pure pyridine solution, preparation of pyridine hydrochloride.

uses    used as pharmaceutical intermediates

pyridine hydrochloride is mainly used in pharmaceutical intermediates, biochemical research, organic synthesis; it is also one of the raw materials for the production of methyl erythromycin.

 

Attribute	Details
Chemical Name	Pyridine Hydrochloride
Synonyms	Pyridinium Chloride; Hydrochloride Pyridine; Pyridine HCl; Pyridine Chlorhydrate; etc.
CAS Number	628-13-7
Molecular Formula	C5H5N·HCl or C5H6ClN
Molecular Weight	115.56 g/mol
Appearance	White or off-white crystalline powder
Physical Properties	Soluble in water and ethanol; insoluble in dichloromethane; Melting Point: 140-147°C (varies slightly depending on source); Boiling Point: 222-224°C; Odor: Pungent, characteristic of pyridine
Chemical Properties	Forms by the reaction of pyridine with hydrochloric acid; Stable under normal temperatures and pressures; Hygroscopic, meaning it readily absorbs moisture from the air
Applications	Used as an intermediate in organic synthesis; Acts as a catalyst in various chemical reactions; Used in the synthesis of pharmaceuticals, such as methylerythromycin, a broad-spectrum antibiotic; Also used in biochemical research and as a precursor in the synthesis of agrochemicals
Safety Information	May cause irritation to skin, eyes, and respiratory system; Handle with caution and follow standard chemical safety procedures; Wear appropriate protective clothing, eye/face protection, and respiratory protection
Storage Conditions	Store in a cool, dry place, away from heat, sparks, and open flames; Keep container tightly closed and protected from light and moisture

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