Pyridine hydrobromide
Pharmaceutical Materials 2025-03-02
CAS Number: 18820-82-1
Molecular Formula: C5H6BrN (or C5H5N·HBr)
Molecular Weight: 160.01 g/mol
Appearance: White to light yellow or light orange powder/crystal
Usage: Used as an intermediate in pharmaceuticals, such as cephalosporin antibiotics, and as a papermaking aid.
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| Category | Details |
|---|---|
| Chemical Name | Pyridine Hydrobromide |
| Synonyms | Pyridinium Bromide, Pyridine Bromide Salt |
| CAS Number | 18820-82-1 |
| Molecular Formula | C5H5N·HBr |
| Molecular Weight | 160.01 g/mol |
| Appearance | White or off-white solid |
| Solubility | Soluble in water and ethanol; insoluble in acetone, chloroform, and aromatic hydrocarbons |
| Melting Point | 217-220°C |
| pH | Aqueous solutions are acidic (pH ~2.65-2.75 for 1g dissolved in 10ml water) |
| Chemical Properties | Forms a strong acid-weak base salt; exhibits typical salt properties such as solubility in polar solvents and stability under normal conditions |
| Synthesis | Prepared by reacting pyridine with hydrogen bromide or bromine in suitable solvents, followed by purification |
| Applications | – Used as an intermediate in the synthesis of pharmaceuticals, particularly cephalosporin antibiotics – Employed as a papermaking aid to improve paper strength and quality – Utilized in organic synthesis for the preparation of various pyridine derivatives |
| Safety | Non-toxic and non-hazardous under normal conditions; however, it should be handled with caution to avoid skin and eye contact. Store in a cool, dry place. |
