protocatechuic acid CAS Number: 99-50-3
Pharmaceutical Materials 2025-03-02
CAS Number: 99-50-3
Molecular Formula: C7H6O4
Molecular Weight: 154.12
Appearance: White to light yellow crystal powder
Usage: Antioxidant (only for reference standard and R&D, not for human)
Protocatechuic acid, with a CAS number of 99-50-3, is a naturally occurring polyphenolic compound. It is abundant in various edible and medicinal plants, particularly as a major metabolite of antioxidant polyphenols found in green tea. This compound exhibits potent antioxidant activity, demonstrated by its ability to scavenge free radicals in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assays. Protocatechuic acid is recognized for its anti-inflammatory, anti-hyperglycemic, neuroprotective, and anti-cancer properties. It also inhibits chemical carcinogenesis in vitro and exerts pro-apoptotic and anti-proliferative effects in different tissues.
| Property | Value |
|---|---|
| CAS Number | 99-50-3 |
| Physical Properties | |
| – Molecular Formula | C7H6O4 |
| – Molecular Weight | 154.12 g/mol |
| – Melting Point | 197-200 °C (decomposition) |
| – Boiling Point | 410.7±35.0 °C at 760 mmHg |
| – Density | 1.6±0.1 g/cm3 |
| Chemical Properties | |
| – Solubility | Soluble in hot water, ethanol, and ether; slightly soluble in cold water; insoluble in benzene |
| – Acidity Coefficient (pKa) | 4.48 (at 25°C) |
| – Refractive Index | 1.671 (estimate) |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
