Pravastatin sodium
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80019089
CAS NO.81131-70-6
Purity 98%
MDL NumberMFCD00887601
Molecular FormulaC23H35NaO7
Molecular Weight446.5096
Melting point: 172~175°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C23H35NaO7, Molecular weight: 446.5 |
| Physical Properties | White crystalline powder, soluble in water |
| Pharmacokinetics | Absorption: Low bioavailability (17%), rapidly absorbed from the small intestine, peak serum concentration reached in 1-1.5 hours.<br> Distribution: Volume of distribution: 0.5 L/kg in adults.<br> Metabolism: Undergoes extensive first-pass metabolism in the liver, primarily metabolized by glucuronidation.<br> Elimination: 70% eliminated in feces, 20% in urine. |
| Mechanism of Action | Inhibits HMG-CoA reductase, reducing cholesterol biosynthesis. Increases LDL receptor activity, enhancing LDL clearance. |
| Therapeutic Uses | Used to lower cholesterol levels and reduce the risk of cardiovascular diseases |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture |
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