Pharmaceutical Materials

CAS No.865-47-4

Name

Potassium tert-butoxide

Synonyms

KTB

PTB

Potassiumtbutoxide

potassium-butoxide

Potassium t-butoxide

Potassium tert-butoxide

Potassium tert-butylate

potassium tert-butanolate

Potassium Tertiary Butoxide

PotassiuM tert-butyl alcohol

BuOk(PotassiuM tert-butoxide)

2-methyl-2-propanopotassiumsalt

potassium 2-methylpropan-2-olate

2-Propanol,2-methyl-,potassiumsalt

N-(2-Chlorobenzyloxycarbonyloxy) succinimide

PotassiuM tert-butoxide solution 1.0 M in THF

PotassiuM tert-butoxide, 1.0 M solution in THF, SpcSeal

PotassiuM tert-butoxide, 1.8 M solution in THF, SpcSeal

PotassiuM tert-butoxide, 1.0 M solution in tert-Butanol , SpcSeal

 

Attribute	Details
Chemical Name	Potassium tert-butoxide
CAS Number	865-47-4
Synonyms	Potassium t-butoxide; t-BuOK; Potassium tert-butylate
Molecular Formula	C4H9KO
Molecular Weight	112.21 g/mol
Appearance	White to off-white solid, may appear as a powder or a crystalline solid
Physical Properties	Density: 0.910 g/mL at 20°C; Melting Point: 256-258°C; Boiling Point: 275°C; Soluble in organic solvents such as hexane, ether, and tetrahydrofuran; reacts vigorously with water
Chemical Properties	Strong base; conjugate acid (tert-butanol) has a pKa of approximately 17; reacts with acids to form potassium salts and tert-butanol; sensitive to moisture and air
Uses	Widely used as a base catalyst in organic synthesis reactions such as ester exchanges, condensations, rearrangements, polymerizations, ring-opening reactions, and the preparation of heavy metal carboxylates; also used in the synthesis of pharmaceutical intermediates and pesticides
Production Methods	Typically produced by reacting potassium metal with tert-butanol in an inert atmosphere; the reaction is exothermic and requires careful control of temperature and stirring
Safety Information	Flammable solid; may self-heat and ignite if stored in large quantities; causes severe skin burns and eye damage; keep away from heat, sparks, and open flames; store in a cool, dry, well-ventilated area; wear appropriate personal protective equipment when handling

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