Pomalidomide-PEG2-butyl iodide
Biomedicine 2025-03-04
CAS NO.: 1835705-72-0
Product purity: ≥95%
Molecular formula: C23H28In3O7
Molecular weight: 585.39
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information
| Item | Description |
|---|---|
| Full Name | Pomalidomide-PEG2-butyl iodide |
| CAS Number | 1835705-72-0 |
| Molecular Formula | C23H28IN3O7 |
| Molecular Weight | 585.39 |
| Purity | ≥95% |
| Appearance | Pale yellow solid or powder |
| Solubility | Soluble in DMSO, DMF, DCM |
| Storage Conditions | 2-8°C, dry, protected from light |
Detailed Information
| Item | Description |
|---|---|
| Structure | Contains a Pomalidomide core linked to a PEG chain with two ethylene oxide units, terminated with a butyl iodide group |
| Reactivity | The butyl iodide group is highly reactive with nucleophilic groups such as amines and thiols, making it suitable for bioconjugation applications |
| Applications | – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers. |
| Advantages | – Combines the properties of Pomalidomide, PEG, and a reactive butyl iodide group.<br>- High biocompatibility and versatility in bioconjugation. |
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