Polypropylene Glycol PPG

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Introduction

CAS25322-69-4

Name

Poly propylene glycol

Synonyms

PPG

poly(oxypropylene)

poly(propene oxide)

Poly propylene glycol

Poly(propylene glycol)

POLYPROPYLENE GLYCOL 400

POLYPROPYLENE GLYCOL 700

POLYPROPYLENE GLYCOL 2000

POLYPROPYLENE GLYCOL 1000

Polypropylene glycol diol

Polypropylene glycol 2000

POLYPROPYLENE GLYCOL P 400

Poly(propylene glycol) 4000

Poly(propylene glycol) 3000

Poly(propylene glycol) 1000

Polypropylene glycol – 2000 grade

polypropylene glycol standard 5300

POLYPROPYLENE GLYCOL, DIOL TYPE, 700

POLYPROPYLENE GLYCOL, DIOL TYPE, 1000

POLYPROPYLENE GLYCOL, DIOL TYPE, 2.000

(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propan-1-ol

(2R)-2-{[(2R)-2-hydroxypropyl]oxy}propan-1-ol

(2R)-2-{[(2S)-2-hydroxypropyl]oxy}propan-1-ol

(2S)-2-{[(2S)-2-hydroxypropyl]oxy}propan-1-ol

Reference Information

LogP    0.01 at 25℃

use limit    for fermentation process, limited to GMP (GB 2760-96).

toxicity    LD50>10 g/kg (mouse, oral).

mutagenicity test, Ames test, mouse bone marrow micronucleus test, mouse sperm aberration test, no abnormalities.

Propylene glycol stimulation of rabbit corneal epithelium will produce temporary slight corneal congestion. If propylene glycol is washed with 50% aqueous solution for 5 minutes to remove propylene glycol, it will not cause any harm, but if it is stimulated with undiluted propylene glycol for 5 minutes, it will produce moderate reaction.

emergency operation    treatment method after contact:

1. inhalation: move to fresh air and rest.

2. Skin contact: remove contaminated clothes and rinse skin or shower with plenty of water.

3. eye contact: open your eyes, rinse with flowing water for 10 minutes, and then see a doctor.

use    defoamer; Solvents for vegetable oil, wax and resin. Used for eucalyptus sugar, beverages, candy, yeast, etc.

Defoamer. Used in the production of yeast, monosodium glutamate, etc. The defoaming efficiency is several to dozens of times that of edible oil.

production method    glycerin and refined propylene oxide are polymerized under the catalysis of potassium hydroxide at a temperature of 90~95 ℃ and a pressure of 0.4 ~ 0.5MPa. Then cool to 60~70 ℃, press the material into a neutralization kettle, add water under stirring to neutralize excess potassium hydroxide, then add phosphoric acid at 60~70 ℃ to neutralize to pH 6~7. then slowly raise the temperature to 110~120 ℃, dehydrate and filter in vacuum.

It is formed by the addition reaction of propylene glycol polymer and water.

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