Polyethylene-polypropylene glycol
Food Additives 2025-03-02
Basic Information
| Attribute | Details |
|---|---|
| CAS Number | 9003-11-6 |
| Molecular Formula | C13H20O8 |
| Molecular Weight | Approximately 304.293 g/mol |
| Common Names | Pluronic F-127. Poloxamer 407. Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) |
Physical Properties
| Property | Value |
|---|---|
| Appearance | White crystalline powder or colorless to yellow transparent oily liquid |
| Density | 1.2±0.1 g/cm³ |
| Melting Point | Approximately 56-60°C |
| Boiling Point | 370.7±37.0°C at 760 mmHg |
| Flash Point | 160.5±26.5°C |
| Solubility | Soluble in cold water, ethanol, acetone, carbon tetrachloride, benzene, and ether |
Chemical Characteristics
Non-ionic surfactant with 100% activity.
Biocompatible and relatively non-toxic to cells.
Exhibits reverse thermal gelation: liquid at low temperatures and gels at body temperature.
Applications
Widely used in molecular biology and pharmacology research.
Acts as an ideal drug delivery material due to its low toxicity, minimal irritation, and good biocompatibility.
Used in genetic therapy and inhibiting postoperative intestinal adhesions.
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