piperazine (medicine) CAS Number: 110-85-0
Pharmaceutical Materials 2025-03-03
CAS Number: 110-85-0
Molecular Formula: C4H10N2
Molecular Weight: 86.14 g/mol
Appearance: White to slightly yellow crystalline solid
Pharmacological Effects: Antihistamine, anticholinergic, anti-ciliary motion, and muscle relaxant.
Usage: Widely used as an antihistamine drug.
Piperazine, with the CAS number 110-85-0, is an important medicinal intermediate primarily used in the production of anthelmintic drugs such as piperazine phosphate and piperazine citrate. It also finds applications in the synthesis of various pharmaceuticals, including antipsychotics and analgesics. Piperazine is a white crystalline powder with a distinct ammoniacal odor. It is soluble in water and ethanol but insoluble in ether. This compound exhibits alkaline reactivity in aqueous solutions. Due to its versatile applications in the pharmaceutical industry, piperazine plays a crucial role in the treatment of intestinal parasitic infections and other medical conditions.
| Property | Value |
|---|---|
| CAS Number | 110-85-0 |
| Physical Properties | |
| – Molecular Formula | C4H10N2 |
| – Molecular Weight | 86.14 g/mol |
| – Appearance | White crystalline powder |
| – Odor | Ammoniacal |
| – Density | 1.1 g/cm³ |
| – Melting Point | 109-112°C |
| – Boiling Point | 146°C |
| – Flash Point | 65°C |
| – Refractive Index | 1.4460 |
| Chemical Properties | |
| – Solubility | Soluble in water, ethanol; insoluble in ether |
| – pH (1M solution in water) | 11.0-12.5 |
| – pKa | 9.83 (at 23°C) |
| – LogP | -1.24 (at 20-25°C) |
| – Reactivity | Alkaline in aqueous solutions |
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