Pharmaceutical Materials

CAS Number: 110-85-0

Molecular Formula: C4H10N2

Molecular Weight: 86.14 g/mol

Appearance: White to slightly yellow crystalline solid

Pharmacological Effects: Antihistamine, anticholinergic, anti-ciliary motion, and muscle relaxant.

Usage: Widely used as an antihistamine drug.

Piperazine, with the CAS number 110-85-0, is an important medicinal intermediate primarily used in the production of anthelmintic drugs such as piperazine phosphate and piperazine citrate. It also finds applications in the synthesis of various pharmaceuticals, including antipsychotics and analgesics. Piperazine is a white crystalline powder with a distinct ammoniacal odor. It is soluble in water and ethanol but insoluble in ether. This compound exhibits alkaline reactivity in aqueous solutions. Due to its versatile applications in the pharmaceutical industry, piperazine plays a crucial role in the treatment of intestinal parasitic infections and other medical conditions.

Property	Value
CAS Number	110-85-0
Physical Properties
– Molecular Formula	C4H10N2
– Molecular Weight	86.14 g/mol
– Appearance	White crystalline powder
– Odor	Ammoniacal
– Density	1.1 g/cm³
– Melting Point	109-112°C
– Boiling Point	146°C
– Flash Point	65°C
– Refractive Index	1.4460
Chemical Properties
– Solubility	Soluble in water, ethanol; insoluble in ether
– pH (1M solution in water)	11.0-12.5
– pKa	9.83 (at 23°C)
– LogP	-1.24 (at 20-25°C)
– Reactivity	Alkaline in aqueous solutions

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