Pikamilone
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID 80020673
CAS NO.34562-97-5
Purity 96%
MDL NumberMFCD00186518
Molecular Formula C10H12N2O3
Molecular Weight 208.2139
Melting point: 210~212°C
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₀H₁₂N₂O₃<br>- Molecular Weight: 208.21 g/mol<br>- CAS Number: 34562-97-5<br>- Synonyms: Nicotinyl-GABA, N-(3-Carboxypropyl)nicotinamide, 4-(Pyridine-3-carbonylamino)butyric acid |
| Physical Properties | – Appearance: White to off-white powder<br>- Melting Point: 180-183°C |
| Mechanism of Action | – Combines niacin (vitamin B3) with GABA (γ-aminobutyric acid) to enhance brain function.<br>- Crosses the blood-brain barrier to release GABA and niacin, improving cerebral blood flow and reducing neuronal excitability. |
| Biological Activities | – Improves cognitive function, reduces anxiety, and enhances mood.<br>- Demonstrates neuroprotective effects and promotes brain health.<br>- Reduces seizure activity in animal models. |
| Applications | – Used in the treatment of anxiety, depression, and cerebrovascular disorders.<br>- Investigated for its potential in treating alcoholism and improving sleep quality.<br>- Used as a nootropic supplement to enhance focus, memory, and mental clarity. |
| Storage Conditions | Store at 4°C, protect from light. |
| Safety Information | – Potential side effects include dizziness, nausea, and headaches.<br>- May interact with other medications, especially those affecting blood pressure.<br>- Not approved by the FDA for use as a dietary supplement. |
| Research Uses | – Widely used in molecular biology and pharmacology research.<br>- Studied for its effects on brain function and mental health |
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