Phenylazomalononitrile Cas：6017-21-6
Pharmaceutical Materials 2025-03-02
Phenylazomalononitrile (CAS No. 6017-21-6) is a yellow solid compound with the molecular formula C9H6N4 and a molecular weight of 170.17 g/mol. It is primarily utilized as a pharmaceutical intermediate in the synthesis of drug molecules with specific pharmacological activities, particularly as an intermediate for riociguat.
The compound’s structure features a substituted benzene ring and a malononitrile group, which may confer unique chemical properties and reactivity. In drug development, this intermediate may undergo multi-step organic synthesis reactions, such as substitution and condensation, to introduce various pharmacophoric groups, thereby generating drug candidates with therapeutic potential. Although direct pharmacological data on this compound are currently limited, its role as a pharmaceutical intermediate suggests that the final product may possess therapeutic value, especially in the treatment of cardiovascular diseases.
| CAS Number | 6017-21-6 |
| Molecular Formula | C9H6N4 |
| Molecular Weight | 170.17 g/mol |
| Appearance | Yellow solid |
| Purity | ≥96% |
| Application | Pharmaceutical intermediate, used in the synthesis of drug molecules with specific pharmacological activities, particularly as an intermediate for riociguat |
| Structure Features | Substituted benzene ring, malononitrile group |
| Synthesis | Multi-step organic synthesis reactions, such as substitution, condensation, etc. Enzymatic catalysis may be involved |
| Pharmacological Activity | Data currently limited, but the final product may have therapeutic value, especially in the treatment of cardiovascular diseases |
| Research Status | Studied in chemical synthesis and drug discovery, with potential applications in the pharmaceutical industry |
| Physical Properties | Density: 1.12 g/cm³, Boiling Point: 260.7°C at 760 mmHg, Melting Point: >130°C, Flash Point: 111.5°C, Refractive Index: 1.592 |
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