Phenidone
Active Pharmaceutical Ingredients 2025-03-03
English Synonyms N-phenylpyrazolidin-3-one
Catalog ID99678
CAS NO.92-43-3
Purity 98%
MDL NumberMFCD00003094
EINEColecular formula C9H10N2O
Molecular weight 162.191
| Category | Content |
|---|---|
| Generic Name | Phenidone (1-phenyl-3-pyrazolidinone) |
| Chemical Formula | C9H10N2O |
| CAS Number | 92-43-3 |
| Mechanism of Action | Phenidone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), inhibiting the synthesis of prostaglandins and leukotrienes. It has anti-inflammatory and antioxidant properties. |
| Biological Activity | – Inhibits COX-1/-2 and 5-LOX in the spinal cords of rats with experimental autoimmune encephalomyelitis (EAE).<br>- Reduces blood pressure in spontaneously hypertensive rats. |
| Applications | – Used as a photographic developer.<br>- Investigated for potential use in inflammatory and neurodegenerative diseases. |
| Physical Properties | – Appearance: Light beige powder or crystals.<br>- Solubility: Soluble in DMSO.<br>- Storage: Store at 4°C, sealed, away from moisture and light. |
| Safety Profile | – Poisonous by ingestion and intraperitoneal routes.<br>- Emits toxic fumes of NOx when heated to decomposition. |
| Synonyms | 1-phenyl-3-pyrazolidinone, Pheaidone |
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