Pharmaceutical Materials

In 2012, all the intermediates supporting β-lactam antibiotics can be produced by ourselves, and all the side-chain intermediates can be produced and exported in large quantities, except for the mother nucleus of semi-synthetic antibiotics, 7-ACA and 7-ADCA, which need to be partially imported. Taking phenylacetic acid as an example, which is the main supporting intermediate of β-lactam antibiotics, there are nearly 30 manufacturers of phenylacetic acid in China, with a total annual production capacity of about 20,000 tons. But most of the enterprises are small in scale, the largest annual output of 2,000 tons, and most of the other annual output of hundreds of tons.In 2003, the total domestic demand for phenylacetic acid is about 14,000 tons, and the consumption structure is as follows: penicillin G accounted for 85%, other pharmaceuticals accounted for 4%, spices accounted for 7%, pesticides and other fields accounted for 4%. With the development of domestic spices, pharmaceuticals, pesticides and other industries, the demand for phenylacetic acid will further increase. It is expected that by 2005, China’s pharmaceutical industry will consume about 14,000 tons of phenylacetic acid, the pesticide industry will consume 500 tons, and the spice industry will consume about 2,000 tons. Together with the consumption in other fields, it is expected that the total domestic demand for phenylacetic acid will reach 18,000 tons in 2005, so it is necessary to strengthen the customization of pharmaceutical intermediates.,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.