Active Pharmaceutical Ingredients

Catalog ID 80071757

CAS NO.107133-36-8

Purity 98+%

MDL NumberMFCD02313824

Molecular Formula C19H32N2O5.C4H11N

Molecular Weight 441.6046

Melting point: 126~130°C

Category	Content
Generic Name	Perindopril Erbumine
Chemical Formula	C23H43N3O5
CAS Number	107133-36-8
Mechanism of Action	Perindopril erbumine is an angiotensin-converting enzyme (ACE) inhibitor. It blocks the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and lowering blood pressure.
Indications	– Treatment of hypertension (high blood pressure).<br>- Prevention of heart attacks and strokes in patients with high blood pressure.<br>- Used in patients with stable coronary artery disease to reduce the risk of cardiovascular events.
Dosage Forms	Tablets (2 mg, 4 mg, 8 mg)
Administration	Taken orally once daily, with or without food. The usual starting dose is 4 mg once daily.
Common Side Effects	– Dry cough.<br>- Dizziness.<br>- Low blood pressure.<br>- Headaches.<br>- Nausea.<br>- Diarrhea.<br>- Mild skin rash.<br>- Blurred vision.
Serious Side Effects	– Angioedema (swelling of the lips, face, tongue, or throat).<br>- Hypotension (low blood pressure) with symptoms like dizziness, fainting, or confusion.<br>- Kidney damage with symptoms like reduced urine output, swelling in the legs, or difficulty breathing.<br>- Hyperkalemia (high potassium levels) with symptoms like muscle weakness, slow heartbeat, or nausea.<br>- Neutropenia (low white blood cell count) with symptoms like fever, sore throat, or frequent infections.<br>- Liver damage with symptoms like nausea, vomiting, jaundice, or dark urine.<br>- Severe allergic reactions with symptoms like breathing problems, swelling, or hives.
Precautions	– Monitor blood pressure and kidney function regularly.<br>- Avoid use in patients with a history of angioedema.<br>- Use with caution in patients with liver or kidney disease.<br>- Inform your doctor if you are pregnant or breastfeeding.
Storage	Store at room temperature, protect from moisture.
Developer	Developed by Servier Pharmaceuticals.

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