pazufloxacin mesylate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020455
CAS NO.163680-77-1
Purity 96%
MDL NumberMFCD00913262
Molecular Formula C17H19FN2SO7
Molecular Weight 414.4
Melting point: >255°C
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₇H₁₉FN₂O₇S<br>- Molecular Weight: 414.41 g/mol |
| Physical Properties | – Appearance: White to off-white powder<br>- Solubility: Soluble in water (≥ 100 mg/mL) and DMSO (100 mg/mL, with sonication) |
| Mechanism of Action | – Fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV.<br>- Exhibits broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria, including quinolone-resistant strains. |
| Clinical Uses | – Respiratory Infections: Chronic bronchitis, pneumonia, lung abscess.<br>- Urinary Tract Infections: Pyelonephritis, complicated cystitis.<br>- Gynecological Infections: Pelvic inflammatory disease, endometritis.<br>- Surgical and Burn Infections: Wound infections, burn surface infections.<br>- Gastrointestinal Infections: Cholecystitis, cholangitis, intra-abdominal abscess. |
| Dosage | – Adults: Intravenous infusion, 0.5 g twice daily, or 0.3 g twice daily for mild cases.<br>- Duration: Typically 7-14 days. |
| Adverse Effects | – Common: Nausea, headache, dizziness.<br>- Rare: Allergic reactions, liver function abnormalities. |
| Contraindications | – Hypersensitivity to pazufloxacin or other quinolones.<br>- Pregnancy and breastfeeding.<br>- Children. |
| Storage Conditions | Store at 4°C, sealed, away from moisture. |
| Synonyms | – Pazufloxacin methanesulfonate<br>- T-3762<br>- Pazucross |
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