
Oxonic acid potassium salt CAS NO.2207-75-2
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Category:Active Pharmaceutical Ingredients MOQ:100KG Shipped directly from China
Introduction
Catalog ID80017060
CAS NO.2207-75-2
Purity 97%
MDL NumberMFCD00010565
EINEC218-627-5
Molecular formula C4H2KN3O4
Molecular weight 195.1747
Aspect | Details |
---|---|
Chemical Structure | – Molecular Formula: C₄H₂KN₃O₄<br>- Molecular Weight: 195.17 |
Mechanism of Action | – Oxonic acid potassium salt is a selective inhibitor of uricase, an enzyme that catalyzes the oxidation of uric acid to allantoin.<br>- It prevents the metabolism and excretion of uric acid, leading to increased uric acid levels. |
Clinical Uses | – Used as a research tool to induce hyperuricemia (high uric acid levels) in animal models.<br>- Component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU), used to suppress gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity. |
Pharmacokinetics | – Solubility: Soluble in water at 9.09 mg/mL (46.57 mM); sonication recommended.<br>- Storage: Powder should be stored at -20°C for up to 3 years; solutions can be stored at -80°C for up to 1 year. |
Physical Properties | – Appearance: White to off-white powder.<br>- Melting Point: 300°C (lit.). |
Safety | – Should be stored in an inert atmosphere at 2-8°C.<br>- Handling and disposal should follow standard laboratory safety protocols. |
Synonyms | – Potassium oxonate<br>- Potassium azaorotate<br>- Potassium otastat |
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