Oseltamivir phosphate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS NO.: 204255-11-8
Molecular formula: C16H31N2O8P
Molecular weight: 410.4
Standard: USP
Content: ≥99.0%
Packaging: 1KG/TIN
Introduction to Oseltamivir Phosphate
| Attribute | Details |
|---|---|
| Chemical Name | (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate phosphate |
| Molecular Formula | C₁₆H₂₈N₂O₄·H₃PO₄ |
| Molecular Weight | 410.40 g/mol |
| Appearance | White to off-white powder (capsule content) |
| Mechanism of Action | Oseltamivir phosphate is a prodrug that is metabolized into its active form, oseltamivir carboxylate, which is a selective inhibitor of influenza virus neuraminidase. It prevents the release of new virus particles from infected cells, thereby reducing viral spread. |
| Clinical Uses | – Treatment of acute, uncomplicated influenza A and B in patients aged ≥1 year, if symptoms have appeared within the past 48 hours.<br>- Prevention of influenza in individuals aged ≥1 year who have been in close contact with infected individuals. |
| Dosage | – Treatment: Adults and children ≥13 years: 75 mg twice daily for 5 days.<br>- Prevention: Adults and children ≥13 years: 75 mg once daily for at least 10 days.<br>- Children: Dosing based on weight. |
| Pharmacokinetics | – Bioavailability: >80%.<br>- Metabolism: Converted to active metabolite in the liver.<br>- Elimination: Primarily excreted in urine. |
| Adverse Effects | Common side effects include nausea, vomiting, headache, and dizziness. |
| Brand Name | Tamiflu |
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