Norfenefrine HCl
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80018919
CAS NO.15308-34-6
Purity 98%
MDL NumberMFCD00012879
EINEC225-323-6
Molecular FormulaC8H11NO2.HCl
Molecular Weight189.64
Melting point: 162~164°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C8H12ClNO2<br> Molecular weight: 189.64 |
| Physical Properties | White to off-white crystalline powder.<br> Melting point: 162–164°C.<br> Soluble in water (50 mg/mL) and DMSO (≥100 mg/mL). |
| Mechanism of Action | Norfenefrine HCl is an orally active, endogenous α-adrenergic agonist. It acts on α-adrenergic receptors to produce sympathomimetic effects. |
| Therapeutic Uses | Used for the treatment of female stress incontinence.<br> Also used as a nasal decongestant and bronchodilator. |
| Storage Conditions | Store at 4°C, protected from moisture. In solvent: -80°C (6 months), -20°C (1 month) under nitrogen. |
| Safety and Handling | Harmful if swallowed (LD50 oral in rats: 390 mg/kg). Irritating to the eyes. |
| Applications | Used in pharmaceutical research and development, particularly in sustained-release dosage forms and nasal sprays |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
