N,N’-Dimethylpiperazine CAS Number: 106-58-1

Pharmaceutical Materials 2025-03-02

CAS Number: 106-58-1

Molecular Formula: C6H14N2

Molecular Weight: 114.19

Appearance: Colorless to light yellow liquid

Melting Point: -1°C

Boiling Point: 130-133°C

Density: 0.844 g/mL at 25°C

Usage: Used as an intermediate in chemical synthesis.

N,N’-Dimethylpiperazine, with the CAS Number 106-58-1, is a colorless volatile liquid that belongs to the piperazine derivatives. It is widely used as an intermediate in organic synthesis and biochemistry, particularly in the synthesis of biologically active molecules and cationic surfactants. This compound exhibits significant alkaline properties and finds applications in the production of polyurethane elastomers, coatings, adhesives, and various surfactant products. However, it is flammable, toxic, and corrosive, thus requiring careful handling and storage away from oxidants and acids.

Property Value
CAS Number 106-58-1
Physical Properties
Molecular Formula C6H14N2
Molecular Weight 114.19 g/mol
Appearance Colorless to yellow liquid
Density 0.844 g/mL at 25 °C
Melting Point -1 °C
Boiling Point 131-132 °C at 750 mmHg
Refractive Index 1.4463 at 20 °C
Flash Point 18 °C (65 °F)
Chemical Properties
Solubility Miscible in water, ethanol, and ether
pH Value 11.4 (in water)
pKa Values pK1: 4.630 (+2); pK2: 8.539 (+1) at 25 °C
Reactivity Sensitive to oxidants and acids; flammable

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