Active Pharmaceutical Ingredients

Catalog ID80017821

CAS NO.4936-47-4

Purity 98+%

MDL NumberMFCD00057257

EINEC Molecular Formula C10H11N3O5S

Molecular Weight 285.2764

Melting point: 182°C

Category	Details
Chemical Properties	Molecular formula: C10H11N3O5S<br> Molecular weight: 285.27 g/mol
Physical Properties	Appearance: Fresh yellow crystals or yellow powder<br> Density: 1.6±0.1 g/cm³<br> Melting point: 176–178°C
Mechanism of Action	Nifuratel is a nitrofuran derivative with broad-spectrum antimicrobial activity. It inhibits nucleic acid synthesis and alters cell membrane permeability in microorganisms, leading to cell death.
Therapeutic Uses	Vulvovaginal Infections: Treats bacterial vaginosis, trichomoniasis, and fungal infections.<br> Urinary Tract Infections: Effective against urinary infections.<br> Gastrointestinal Infections: Treats giardiasis and amoebiasis.
Formulations	Available as oral tablets, vaginal suppositories, and topical formulations.
Safety and Side Effects	Common Side Effects: Gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness.<br> Serious Side Effects: Rare but include hypersensitivity reactions, liver toxicity, and hematologic abnormalities.<br> Contraindications: Hypersensitivity to the drug or its components, severe liver or kidney impairment.<br> Pregnancy and Lactation: Use with caution under medical supervision.
Storage Conditions	Store in a cool, dry place, protected from light and moisture.
Synonyms	Macmiror, Methylmercadone, Thiodinon

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