Nifuratel CAS NO.4936-47-4
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017821
CAS NO.4936-47-4
Purity 98+%
MDL NumberMFCD00057257
EINEC Molecular Formula C10H11N3O5S
Molecular Weight 285.2764
Melting point: 182°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C10H11N3O5S<br> Molecular weight: 285.27 g/mol |
| Physical Properties | Appearance: Fresh yellow crystals or yellow powder<br> Density: 1.6±0.1 g/cm³<br> Melting point: 176–178°C |
| Mechanism of Action | Nifuratel is a nitrofuran derivative with broad-spectrum antimicrobial activity. It inhibits nucleic acid synthesis and alters cell membrane permeability in microorganisms, leading to cell death. |
| Therapeutic Uses | Vulvovaginal Infections: Treats bacterial vaginosis, trichomoniasis, and fungal infections.<br> Urinary Tract Infections: Effective against urinary infections.<br> Gastrointestinal Infections: Treats giardiasis and amoebiasis. |
| Formulations | Available as oral tablets, vaginal suppositories, and topical formulations. |
| Safety and Side Effects | Common Side Effects: Gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness.<br> Serious Side Effects: Rare but include hypersensitivity reactions, liver toxicity, and hematologic abnormalities.<br> Contraindications: Hypersensitivity to the drug or its components, severe liver or kidney impairment.<br> Pregnancy and Lactation: Use with caution under medical supervision. |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture. |
| Synonyms | Macmiror, Methylmercadone, Thiodinon |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
