NH2-PEG12-OH CAS NO.: 933789-97-0
Biomedicine 2025-03-04
CAS NO.: 933789-97-0
Product purity: ≥95%
Molecular formula: C24H51NO12
Molecular weight: 545.667
Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
NH2-PEG12-OH: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | NH2-PEG12-OH (Amino-PEG12-Alcohol) |
| CAS Number | 933789-97-0 |
| Molecular Formula | C₂₄H₅₁NO₁₂ |
| Molecular Weight | 545.66 g/mol |
| Appearance | Solid or viscous liquid, depending on molecular weight |
| Solubility | Soluble in water, DMSO, DCM, DMF, and other organic solvents |
| Storage Conditions | Store at -20°C, keep dry and avoid light |
| Purity | ≥95% |
NH2-PEG12-OH: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | Amino-PEG12-alcohol, H2N-PEG24-OH, Amino-PEG36-alcohol, NH2-PEG12-OH, Amino-dPEG(R)12-OH, Amino-PEGn-alcohol (n=12,24,36) |
| Structure | – PEG Chain: Provides hydrophilicity and biocompatibility.<br>- Amine Group: Reactive group that can form amide bonds with carboxylic acids, NHS esters, and other amine-reactive groups.<br>- Hydroxyl Group: Reactive group that can form ester bonds with carboxylic acids. |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and other biomolecules by forming stable amide bonds with primary amines.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Amine Group: Reacts with carboxylic acids, NHS esters, and other amine-reactive groups.<br>- Hydroxyl Group: Reacts with carboxylic acids to form ester bonds. |
| Packaging and Price | – Available in various packaging sizes (e.g., 100mg, 250mg, 500mg, 1g, 5g).<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use. |
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