NH2-PEG-COOH
Biomedicine 2025-03-04
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information of NH2-PEG-COOH
| Item | Description |
|---|---|
| Full Name | Amino Polyethylene Glycol Carboxylic Acid |
| CAS Number | 139729-28-5 |
| Molecular Formula | (C2H4O)nC4H9NO3 |
| Molecular Weight | Commonly available: 500, 1000, 2000, 3400, 5000 |
| Purity | ≥95% |
| Appearance | White or off-white solid |
| Solubility | Soluble in water, methanol, ethanol, DMSO, DMF |
| Storage Conditions | -20°C, dry, protected from light |
Detailed Information of NH2-PEG-COOH
| Item | Description |
|---|---|
| Structure | PEG chain with an amino group (-NH2) at one end and a carboxyl group (-COOH) at the other end |
| Reactivity | -NH2 can react with carboxyl groups to form amide bonds; -COOH can react with amines or alcohols to form esters or amides |
| Applications | – Bioconjugation: Modifies proteins, peptides, and other biomolecules to improve stability and reduce immunogenicity.<br>- Drug Delivery: Used to attach drugs to PEG chains, enhancing drug stability and circulation time.<br>- Surface Modification: Modifies nanoparticles or materials to improve biocompatibility and functionality.<br>- Biosensor Development: Used to immobilize biomolecules for high-sensitivity detection. |
| Advantages | High biocompatibility, good water solubility, and versatile reactivity |
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