Active Pharmaceutical Ingredients

Catalog ID80018013

CAS NO.23327-57-3

Purity 98%

MDL NumberMFCD00012750

Molecular FormulaC17H19NO.HCl

Molecular Weight289.7998

Melting point: 260~262°C

Category	Details
Chemical Properties	Molecular formula: C17H20ClNO<br> Molecular weight: 301.81
Physical Properties	Appearance: White to off-white solid<br> Melting point: 238–242°C (salt form)
Mechanism of Action	Nefopam is a centrally acting analgesic of the benzoxazocine class. It is a non-opioid but has a potentiating effect on morphine and other opioids. Its mechanism of action may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor.
Therapeutic Uses	Analgesic: Used for moderate to severe pain, including postoperative pain, cancer pain, and acute trauma pain.<br> Other Uses: Also used for visceral pain such as acute gastritis, biliary colic, and renal colic.
Pharmacokinetics	Extensively metabolized in the liver to produce active metabolites. Mainly excreted in the urine.
Storage Conditions	Store in a cool, dry place, protected from light and moisture.
Safety Information	Side Effects: Commonly reported side effects include somnolence, nausea, sweating, dizziness, and headache.<br> Drug Interactions: Avoid with MAOIs; increased risk of side effects with tricyclic antidepressants.<br> Contraindications: Not recommended for patients with severe liver or kidney dysfunction.
Synonyms	Nefopam hydrochloride, Fenazoxine hydrochloride, Acupan

Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.