Naproxen sodium CAS NO.26159-34-2
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017785
CAS NO.26159-34-2
Purity 98+%
MDL NumberMFCD00058507
EINEC Molecular Formula C14H13NaO3
Molecular Weight 252.241
Melting point: 259~ 262°C
| Aspect | Details |
|---|---|
| Mechanism of Action | Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits both COX-1 and COX-2 enzymes, reducing the production of prostaglandins responsible for pain and inflammation. |
| Adverse Effects | – Gastrointestinal: Increased risk of bleeding, ulcers, and perforation, especially in patients with a history of stomach ulcers, older adults, or those taking high doses.<br>- Cardiovascular: May increase the risk of heart attack or stroke, particularly with long-term use or in patients with existing heart disease.<br>- Liver and Kidney: Can cause liver damage (hepatotoxicity) and kidney problems, including reduced urine output and swelling.<br>- Other: May cause hypertension, heart failure, hyperkalemia, severe skin reactions (e.g., Stevens-Johnson syndrome), and allergic reactions. |
| Discontinuation | If experiencing severe side effects such as chest pain, difficulty breathing, or signs of liver or kidney problems, discontinue use and seek medical attention immediately. |
| Special Considerations | – Pregnancy: Use during the later part of pregnancy can harm the unborn baby.<br>- Surgery: Inform your doctor if you are taking naproxen sodium before any surgical procedure.<br>- Monitoring: Regular blood pressure and liver function monitoring are recommended, especially with long-term use |
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