Naftifine HCl
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017972
CAS NO.65473-14-5
Purity 99%
MDL NumberMFCD00059047
Molecular Formula C21H21N.HCl
Molecular Weight 323.8591
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C21H21ClN<br> Molecular weight: 337.86 g/mol |
| Physical Properties | Appearance: White crystalline powder |
| Mechanism of Action | Inhibits fungal squalene epoxidase, disrupting ergosterol synthesis and causing fungal cell death. |
| Therapeutic Uses | Indications: Treats fungal skin infections such as ringworm, athlete’s foot, and jock itch.<br> Spectrum of Activity: Effective against dermatophytes (e.g., Trichophyton, Microsporum), yeasts (e.g., Candida albicans), and other fungi. |
| Formulations | Available as 1% and 2% creams and gels for topical use. |
| Dosage | Apply a thin layer once daily for cream or twice daily for gel, until symptoms resolve. |
| Side Effects | Common: Burning, stinging, itching, redness, dry skin.<br> Rare: Allergic reactions (rash, swelling, difficulty breathing). |
| Storage Conditions | Store at room temperature, protect from moisture and light. |
| Brand Names | Naftin, Exodermil |
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