Pharmaceutical Materials

CAS Number: 18156-74-6

Molecular Formula: C6H12N2Si

Molecular Weight: 140.26 g/mol

Appearance: Clear colorless to yellow liquid

Melting Point: -42°C

Boiling Point: 93-94°C (13 mmHg)

Usage: Used as an antibiotic intermediate and a strong silylating agent.

 

Property/Characteristic	Details
Chemical Name	N-(Trimethylsilyl)imidazole
CAS Number	1815-17-4
Synonyms	1-Trimethylsilylimidazole, TMSI, Trimethylsilylimidazole
Molecular Formula	C6H12N2Si
Molecular Weight	144.26 g/mol
Appearance	Colorless to pale yellow liquid
Boiling Point	168-170°C (760 mmHg)
Density	0.89 g/mL at 25°C
Flash Point	55°C
Refractive Index	1.466-1.468 at 20°C
Solubility	Soluble in organic solvents such as toluene, ether, and tetrahydrofuran
Stability	Stable under normal conditions; reacts with water to form imidazole and trimethylsilanol
Hazard Information	Flammable; irritating to eyes, skin, and respiratory system; may cause severe burns; keep away from sources of ignition and incompatible materials
Primary Uses	Used as a silylating agent in organic synthesis, particularly for the protection of hydroxyl and amino groups; also used as a catalyst in condensation reactions and for the preparation of silicon-containing polymers
Handling Precautions	Wear appropriate personal protective equipment; handle in a well-ventilated area; avoid contact with skin, eyes, and clothing; store in a cool, dry place away from incompatible materials and sources of ignition

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