N-tert-Butyl-alpha-phenylnitrone
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80021484
CAS NO.3376-24-7
Purity 98%
MDL NumberMFCD00008799
Colecular formula C11H15NO
Molecular weight 177.245
| Item | Information |
|---|---|
| Chemical Name | N-tert-Butyl-α-phenylnitrone |
| CAS Number | 3376-24-7 |
| Molecular Formula | C₁₁H₁₅NO |
| Molecular Weight | 177.24 |
| Physical Properties | – Melting Point: 71-75°C <br> – Boiling Point: 283.3°C <br> – Density: 0.99 g/cm³ <br> – Refractive Index: 1.552 |
| Solubility | Soluble in DMSO |
| Storage Conditions | Store at 2-8°C |
| Mechanism of Action | – Acts as a nitrone-based free radical scavenger, forming nitroxide spin adducts.<br> – Inhibits COX2 catalytic activity.<br> – Penetrates the blood-brain barrier. |
| Biological Activity | – Effective ROS scavenging.<br> – Anti-inflammatory, neuroprotective, anti-aging, and anti-diabetic properties. |
| Safety Information | – Not classified as a hazardous substance under GHS.<br> – For research use only. |
| Applications | – Used as a free radical trap in research.<br> – Investigated for potential use in neuroprotection and anti-inflammatory applications |
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