N-(Chloromethyl)phthalimide
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Category：Agrochemicals Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
N-(Chloromethyl)phthalimide (CAS No. 17564-64-6)
1. Basic Information
- IUPAC Name: 2-(Chloromethyl)isoindoline-1,3-dione
- Synonyms:
- N-Chloromethylphthalimide
- Phthalimidomethyl chloride
- CAS Number: 17564-64-6
- Molecular Formula: C₉H₆ClNO₂
- Molecular Weight: 195.60 g/mol
- Appearance: White to off-white crystalline powder
- Odor: Odorless
2. Physical and Chemical Properties
| Property | Value |
|---|---|
| Melting Point | 135–138°C (275–280°F) |
| Solubility | – Water: Insoluble |
| – Organic solvents: Soluble in DMF, THF, chloroform | |
| Stability | Moisture-sensitive (hydrolyzes slowly) |
3. Chemical Structure
O
║
◯-N-CH₂-Cl
║
O
(◯ = benzene ring fused at positions 1 & 2)
4. Hazards (GHS Classification)
- Acute Toxicity:
- Harmful if swallowed (H302)
- Causes skin irritation (H315)
- Causes serious eye irritation (H319)
- Sensitization: May cause allergic skin reaction (H317)
- Environmental: Toxic to aquatic life (H411)
- NFPA Rating: Health 2, Flammability 1, Reactivity 1
5. Storage and Handling
- Storage:
- Keep in airtight containers under inert gas (N₂)
- Store at 2–8°C protected from moisture
- Handling:
- Use nitrile gloves, face shield, and fume hood
- Avoid contact with water/alcohols
6. Applications
- Organic Synthesis:
- Alkylating agent for amine protection (Emoc-type chemistry)
- Intermediate for pharmaceuticals (e.g., GABA analogs)
- Polymer Chemistry:
- Crosslinking agent for specialty resins
Disclaimer:
The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
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