N-Butyl Lithium CAS No. 109-72-8
Pharmaceutical Materials 2025-03-18
| Aspect | Details |
|---|---|
| Product Name | N-Butyl Lithium |
| Chemical Name | n-Butyllithium |
| CAS Number | 109-72-8 |
| Chemical Formula | C₄H₉Li |
| Molecular Weight | 64.05 g/mol |
| Physical State | Colorless to pale yellow liquid |
| Density | 0.68 g/mL at 20°C |
| Melting Point | -95°C |
| Boiling Point | 60–80°C |
| Flash Point | -21°C |
| Solubility | Soluble in non-polar solvents like hexane, cyclohexane, and ether |
| Reactivity | Highly reactive with water, air, and protic solvents; pyrophoric in air |
| Main Uses | – Strong base and nucleophile in organic synthesis for deprotonation reactions. – Initiator for anionic polymerization of monomers such as styrene and butadiene. – Key reagent in metalation reactions to form organolithium compounds. – Used in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. |
| Packaging | Typically available in solutions of 1.6 M, 2.5 M, or higher concentrations in hexane or cyclohexane |
| Storage Conditions | Stored under inert gas (nitrogen or argon) in a cool, dry place away from moisture and air |
| Safety Precautions | Requires strict handling under inert atmosphere; use of protective gear (gloves, goggles, lab coat) is mandatory |
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