N-Amino-3-Aza-Bicyclo[3,3,0]octane Hydrochloride CAS No.:580108-05-7
Pharmaceutical Materials 2025-03-20
N-Amino-3-Aza-Bicyclo[3,3,0]octane Hydrochloride (CAS No. 58108-05-7) is a key intermediate in pharmaceutical synthesis, particularly for antidiabetic drugs like Gliclazide. With a molecular formula of C7H15ClN2 and a molecular weight of 162.66 g/mol, it appears as a grayish-white to light beige solid. This compound is slightly soluble in chloroform, DMSO, methanol, and water. Its melting point ranges from 170 to 174°C, indicating high thermal stability. Stored under inert atmosphere at room temperature, it demonstrates minimal hygroscopicity. Safety data classifies it as Xi (irritant) with hazard statements H315, H319, and H335, requiring protective measures such as dust masks, eye shields, and gloves during handling. Its role in pharmaceutical chemistry underscores its importance in producing medically relevant compounds.
Chemical Name: N-Amino-3-Aza-Bicyclo[3,3,0]octane Hydrochloride
Assay: ≥99.0%
Usage：Organic synthesis. Making medicines and dyes
Packaging and Shipping：25KG/drum or as per buyer’s requirements
| Name | N-Amino-3-Aza-Bicyclo[3,3,0]octane Hydrochloride |
| CAS No. | 58108-05-7 |
| Molecular Formula | C₇H₁₅ClN₂ |
| Molecular Weight | 162.66 g/mol |
| Appearance | White to light tan powder |
| Purity | ≥99% (HPLC verified) |
| Applications | Pharmaceutical intermediate (Gliclazide synthesis), organic synthesis, materials science |
| Synthesis | Multi-step process from 1,2-cyclopentanedicarboxylic anhydride, yield ≥97% |
| QC Standards | Purity ≥99%, residual solvents <0.5%, heavy metals <10 ppm |
| Storage | Sealed, cool (room temperature), dry conditions |
| Packaging | 1g, 5g, 25g, 1kg (customizable) |
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