N-acetyl-3-5-diiodo-L-tyrosine
N-acetyl-3-5-diiodo-L-tyrosine – Names and Identifiers
Name
N-acetyl-3-5-diiodo-L-tyrosine
Synonyms
AC-3,5-DIIODO-TYR-OHN-Acetyl-3,5-diiodotyrosineN-Acetyl-3,5-diiodo-L-tyrosineN-ACETYL-...
Category：Other Chemicals
Introduction
N-acetyl-3-5-diiodo-L-tyrosine – Names and Identifiers
| Name | N-acetyl-3-5-diiodo-L-tyrosine |
| Synonyms | AC-3,5-DIIODO-TYR-OH N-Acetyl-3,5-diiodotyrosine N-Acetyl-3,5-diiodo-L-tyrosine N-ACETYL-3,5-DIIODO-L-TYROSINE N-acetyl-3-5-diiodo-L-tyrosine 3,5-Diiodo-N-Acetyl-L-Tyrodine 3,5-DIIODO-N-ACETYL-L-TYROSINE N-Acetyl-3,5-Diiodo-L-tyrosine dihydrate 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid 2-(Acetylamino)-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid (2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid Levothyroxine Related Compound (N-Acetyl-3,5-Diiodo-L-Tyrosine) |
| CAS | 1027-28-7 |
| EINECS | 213-837-3 |
| InChI | InChI=1/C11H11I2NO4/c1-5(15)14-9(11(17)18)4-6-2-7(12)10(16)8(13)3-6/h2-3,9,16H,4H2,1H3,(H,14,15)(H,17,18)/t9-/m0/s1 |
N-acetyl-3-5-diiodo-L-tyrosine – Physico-chemical Properties
| Molecular Formula | C11H11I2NO4 |
| Molar Mass | 475.02 |
| Density | 2.206±0.06 g/cm3(Predicted) |
| Melting Point | 124.0 to 128.0 °C |
| Boling Point | 532.9±50.0 °C(Predicted) |
| Flash Point | 276.1°C |
| Solubility | almost transparency in Methanol |
| Vapor Presure | 3.47E-12mmHg at 25°C |
| Appearance | Crystallization |
| Color | White to Light yellow to Light orange |
| pKa | 2.98±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.692 |
| MDL | MFCD00020004 |
| Physical and Chemical Properties |
Property description: white crystalline compound, melting point 178-182 ℃ |
| Use | Iodothyronin (triiodothyronine) intermediate, pharmaceutical raw material. |
N-acetyl-3-5-diiodo-L-tyrosine – Risk and Safety
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
N-acetyl-3-5-diiodo-L-tyrosine – Introduction
Crystalline compound.
N-acetyl-3-5-diiodo-L-tyrosine – Reference Information
| Uses | N-acetyl -3, 5-diiodo-L-tyrosine has been used in the simulation system of thyroid hormone biosynthesis. In addition, the ability of N-acetyl -3, 5-diiodo-L-tyrosine to inhibit pepsin-catalyzed hydrolysis was also studied to determine the substrate binding region of the enzyme activity center. Triiodothyronine intermediate. |
| production method | tyrosine is first iodized with iodine and hydrochloric acid to generate 3,5-diiodotyrosine, and then acylated with acetic anhydride to obtain the product. |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
