N-Acetanilide
Pharmaceutical Materials 2025-03-02
CAS Number: 103-84-4
Molecular Formula: C8H9NO
Molecular Weight: 135.16 g/mol
Appearance: White or grayish crystalline powder Usage: Used as an intermediate in the production of sulfonamides, rubber accelerators, dyes, and synthetic camphor.
| Name | N-Acetylaniline |
| Synonyms | ACETANIL Antifebrin ACETANILIDE Acetanilide ‘LGC’ (4002) ‘LGC’ (2605) ACETYLANILINE N-Acetylaniline N-Phenylacetamide AKOS BBS-00004291 ACETYLAMINOBENZENE ACETIC ACID ANILIDE N-(4-fluorophenyl)acetamide Acetanilide,(N-Phenylacetamide) |
Physico-chemical Properties
| Molecular Formula | C8H9NO |
| Molar Mass | 135.16 |
| Density | 1,121 g/cm3 |
| Melting Point | 113-115°C(lit.) |
| Boling Point | 304°C(lit.) |
| Flash Point | 173 °C |
| Water Solubility | 5 g/L (25 ºC) |
| Solubility | Slightly soluble in water; very soluble in ethanol and acetone; soluble in ethyl ether. |
| Vapor Presure | 1 mm Hg ( 114 °C) |
| Vapor Density | 4.65 (vs air) |
| Appearance | Powder |
| Color | Off-white to beige to grayish-blue |
| Merck | 14,50 |
| BRN | 606468 |
| pKa | 0.5(at 25℃) |
| PH | 5-7 (10g/l, H2O, 25℃) |
| Storage Condition | Store below +30°C. |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, caustics, alkalies. |
| Refractive Index | 1.5700 (estimate) |
| Physical and Chemical Properties | Character white lustrous Flake crystal or white crystalline powder. Odorless. melting point 114.3 ℃ boiling point 304 ℃ relative density 1.2190 flash point 173.9 ℃ solubility slightly soluble in cold water, soluble in hot water, methanol, ethanol, ether, chloroform, acetone, glycerol and benzene. |
| Use | Sulfonamides, rubber vulcanization accelerator, dyes and synthetic camphor and other raw materials and intermediates, cosmetics industry hydrogen peroxide stabilizer |
Risk and Safety
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 – Do not breathe dust. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| WGK Germany | 1 |
| RTECS | AD7350000 |
| TSCA | Yes |
| HS Code | 29242995 |
| Toxicity | LD50 intragastric in rats: 800 mg/kg (Smith, Hambourger) |
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