Pharmaceutical Materials

CAS Number: 82911-69-1

Molecular Formula: C19H15NO5

Molecular Weight: 337.33

Appearance: White to grayish powder

Melting Point: 150-153°C

Use: Mainly used as a pharmaceutical intermediate.

 

Attribute	Details
Chemical Name	N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Other Names	Fmoc-OSu; 9-Fluorenylmethyloxycarbonyl succinimide; Fmoc succinimidyl ester
CAS Registry Number	71989-28-9
Molecular Formula	C20H15NO5
Molecular Weight	349.34 g/mol
Structural Formula	
Appearance	White to light yellow crystalline solid
Melting Point	135-140°C (decomposition)
Solubility	Soluble in organic solvents such as dichloromethane, chloroform, and acetonitrile; insoluble in water
Function	Acts as a versatile reagent for the introduction of the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group to amines
Application	Widely used in solid-phase peptide synthesis and solution-phase peptide synthesis; also employed in the synthesis of amino acid derivatives and peptides
Stability	Stable under normal conditions; however, it is sensitive to moisture and should be stored in a cool, dry place
Safety Information	May cause skin and eye irritation; wear appropriate protective clothing, gloves, and eye protection; handle with care and follow safety instructions

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