Mycophenolate mofetil CAS NO.128794-94-5
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017781
CAS NO.128794-94-5
Purity 98%
MDL NumberMFCD00867568
Molecular FormulaC23H31NO7
Molecular Weight433.4947
Melting point: 93~97°C
| Aspect | Details |
|---|---|
| Mechanism of Action | Mycophenolate mofetil (MMF) is an immunosuppressive agent that is hydrolyzed to its active metabolite, mycophenolic acid (MPA). MPA selectively inhibits inosine monophosphate dehydrogenase (IMPDH), reducing the formation of guanosine nucleotides, which are essential for DNA and RNA synthesis. This inhibits the proliferation of T and B lymphocytes, reducing the immune response. |
| Storage Conditions | – Capsules and Tablets: Store at room temperature (15° to 30°C; 59° to 86°F).<br>- Oral Suspension: Store the dry powder at room temperature (15° to 30°C; 59° to 86°F). After constitution, store at room temperature (15° to 30°C; 59° to 86°F) for up to 60 days or refrigerate at 2° to 8°C (36° to 46°F); do not freeze.<br>- Intravenous Formulation: Store the powder and reconstituted/infusion solutions at room temperature (15° to 30°C; 59° to 86°F). |
| Legal and Regulatory Status | MMF is approved by the US Food and Drug Administration (FDA) for the prevention of organ rejection in patients receiving renal, cardiac, or hepatic transplants. It is also used to treat autoimmune diseases such as lupus and rheumatoid arthritis |
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