mPEG25-SPA CAS NO.: 756525-94-7
Biomedicine 2025-03-04
CAS NO.: 756525-94-7
Product purity: ≥95%
Molecular formula: C58H111NO30
Molecular weight: 1301
Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
mPEG25-SPA: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | mPEG25-SPA (Methoxy Polyethylene Glycol-Succinimidyl Propionate) |
| CAS Number | 756525-94-7 |
| Molecular Formula | C₅₈H₁₁₁NO₃₀ |
| Molecular Weight | 1301 g/mol |
| Appearance | White solid or viscous liquid, depending on molecular weight |
| Solubility | Soluble in water and most organic solvents (e.g., DMSO, DMF, ethanol) |
| Storage Conditions | Store at -5°C, keep dry and avoid light |
| Purity | ≥95% |
mPEG25-SPA: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | mPEG25-NHS, Methyl-PEG25-NHS ester, mPEG25-CH2CH2COONHS ester |
| Structure | – PEG Chain: Provides hydrophilicity and biocompatibility.<br>- NHS Ester Group: Reactive group that can form stable amide bonds with primary amines (-NH2). |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and other biomolecules by forming stable amide bonds with primary amines.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – NHS Ester Group: Reacts with primary amines to form stable amide bonds (pH 7-9).<br>- PEG Chain: Provides hydrophilicity and reduces protein adsorption. |
| Packaging and Price | – Available in various packaging sizes (e.g., 100mg, 250mg, 500mg, 1g, 5g).<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
