Active Pharmaceutical Ingredients

Polyethylene glycol derivatives have the following characteristics:

1) Polymer PEG derivative products generally refer to the use of polyethylene glycol as a raw material for polymers, and various chemical bond reactions are carried out to connect different active groups on both sides of the polymer PEG;

2) PEGylation technology is an advanced pharmaceutical macromolecule modification technique, in which polyethylene glycol molecules are linked to drug molecules to increase the relative molecular weight of the drug, thereby prolonging its efficacy, reducing toxicity, and increasing its water solubility. PEGylation technology is an important means of improving the clinical efficacy of drugs;

3) The molecular weight of this type of product is relatively large, mainly depending on the molecular weight of PEG. The quality of this type of product cannot be measured by purity, so PEG is a polymer and the entire product has a molecular weight distribution.

Methoxypolyethylene glycol polycaprolactone (mPEG PCL) can be used as a carrier material for various drugs. Applied in pharmaceutical research, drug sustained-release, nano new material research, and cell culture. When taking it out of the refrigerator, place it in a dry place and let it slowly rise to room temperature. Prepare it for immediate use, fill it with inert gas after use, and promptly store it in a low-temperature environment. Long term storage requires drying at -20 ℃ and avoiding light.

Methoxypolyethylene glycol polycaprolactone (mPEG PCL) is a block copolymer consisting of a hydrophilic segment methoxypolyethylene glycol at one end and an oleophilic segment polycaprolactone at the other end. By adjusting the molecular weight or hydrophilic/lipophilic segment ratio, methoxypolyethylene glycol polycaprolactone can be used as a carrier material for different types of drugs.

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