mPEG-CHO
Biomedicine 2025-03-04
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information of mPEG-CHO
| Item | Description |
|---|---|
| Full Name | Methoxy Polyethylene Glycol-Aldehyde |
| CAS Number | 125061-88-3 |
| Molecular Weight | Commonly available: 350, 550, 750, 1k, 2k, 5k, 10k, 20k |
| Purity | ≥95% |
| Appearance | White/off-white solid or viscous liquid, depending on molecular weight |
| Solubility | Soluble in water, ethanol, chloroform, DMSO |
| Storage Conditions | -20°C, dry, protected from light |
Detailed Information of mPEG-CHO
| Item | Description |
|---|---|
| Structure | Consists of a methoxy (OCH3) group at one end of the PEG chain and an aldehyde (CHO) group at the other end |
| Reactivity | The aldehyde group reacts with primary amines to form Schiff bases, which can be further reduced to form stable C-N bonds. It can also react with thiol groups and other nucleophiles |
| Applications | – Bioconjugation: Modifies proteins, peptides, and nucleic acids to improve stability and reduce immunogenicity.<br>- Drug Delivery: Enhances drug stability and circulation time in the body.<br>- Surface Modification: Improves the biocompatibility of nanoparticles and other materials.<br>- Biosensors: Used to immobilize biomolecules for high-sensitivity detection |
| Advantages | High biocompatibility, good water solubility, and versatile reactivity |
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