Molnupiravir
Active Pharmaceutical Ingredients 2025-03-03
English Synonyms ((2R,3S,4R,5R)-3,4-Dihydroxy-5-((Z)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate Catalog ID101595 CAS NO.2492423-29-5 Purity 95% MDL NumberMFCD32663515 EINEC Molecular FormulaC13H19N3O7 Molecular Weight329.31
MOLNUPIRAVIR: TECHNICAL DATA SHEET
| Category | Specifications |
|---|---|
| Generic Name | Molnupiravir |
| CAS No. | 2349386-89-4 |
| Molecular Formula | C₁₃H₁₉N₃O₇ |
| Molecular Weight | 329.3 g/mol |
| Appearance | White to off-white powder |
| Solubility | Sparingly soluble in water |
Key Properties
| Property | Performance Data |
|---|---|
| Mechanism of Action | RNA-dependent RNA polymerase inhibitor |
| Antiviral Spectrum | SARS-CoV-2 (COVID-19) |
| Bioavailability | ~30% (oral) |
| Half-life | 3.3 hours |
| Storage Conditions | 20-25°C (protected from moisture) |
Clinical Data
| Parameter | Details |
|---|---|
| Indication | Mild-to-moderate COVID-19 (high-risk adults) |
| Dosage | 800 mg every 12 hours (5 days) |
| Efficacy | 30% risk reduction in hospitalization |
| FDA Approval | EUA (Dec 2021) |
Safety & Compliance
| Aspect | Details |
|---|---|
| Pregnancy Category | Contraindicated (teratogenic risk) |
| Common Side Effects | Diarrhea, nausea |
| Drug Interactions | Limited data |
References:
- FDA EUA Fact Sheet (2022)
- NEJM 2021;385:509-520
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