Mitiglinide calcium salt dihydrate
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80019170
CAS NO.207844-01-7
Purity 98%
MDL NumberMFCD08460208
Molecular FormulaC38H48CaN2O6.2H2O
Molecular Weight 704.91
Melting point: 179~185℃
| Category | Details |
|---|---|
| Chemical Properties | White solid with a molecular formula of C38H52CaN2O8 and a molecular weight of 704.91. |
| Physical Properties | Melting point: 179–185°C. Density: 1.175 g/cm³. |
| Solubility | Slightly soluble in methanol. |
| Pharmacological Effects | Mitiglinide calcium salt dihydrate is an insulinotropic agent that stimulates insulin secretion by closing ATP-sensitive K+ channels in pancreatic beta-cells, resulting in cell depolarization and increased intracellular Ca2+ levels. It is used to treat type 2 diabetes by improving postprandial hyperglycemia. |
| Mechanism of Action | Binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channels in pancreatic beta-cells, promoting insulin secretion. |
| Storage Conditions | Store in an inert atmosphere at room temperature. |
| Safety and Handling | Irritating to eyes, respiratory system, and skin. Protective clothing should be worn when handling |
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