Miconazole Nitrate CAS 3810 74 0
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Category：Active Pharmaceutical Ingredients | Brand：MT
Introduction
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CAS 3810 74 0
| Title | Content |
|---|---|
| Introduction | Miconazole Nitrate is a widely used antifungal medication available in various forms such as creams, gels, powders, and suppositories. It is commonly known by brand names like Daktarin, Monistat, and Lotrimin. |
| Mechanism of Action | Miconazole Nitrate works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This disrupts the integrity of the fungal cell membrane, leading to fungal cell death. |
| Medical Uses | – Skin Infections: Effective for treating ringworm, athlete’s foot, and jock itch.<br>- Vaginal Yeast Infections: Available as suppositories or creams for treating yeast infections.<br>- Nail Infections: Used for fungal infections of the nails. |
| Dosage Forms | – Topical Creams/Gels: Applied directly to the affected skin, typically twice daily.<br>- Suppositories: Used for vaginal infections, usually inserted once a day.<br>- Powders: Sprinkled on affected areas for conditions like athlete’s foot. |
| Common Side Effects | – Skin Irritation: Burning, itching, or redness at the application site.<br>- Vaginal Discomfort: Irritation, itching, or burning sensation during treatment.<br>- Systemic Effects: Rare but may include headache or nausea. |
| Serious Side Effects | – Allergic Reactions: Rash, swelling (especially of the face or throat), difficulty breathing.<br>- Severe Skin Reactions: Persistent irritation or worsening of symptoms. |
| Precautions | – Allergies: Inform your doctor if you are allergic to azole antifungals.<br>- Medical History: Disclose any history of diabetes, circulation problems, or liver/kidney issues.<br>- Pregnancy and Breastfeeding: Consult your doctor before use. |
| Storage Conditions | Store at room temperature, avoid freezing and protect from heat or open flame. |
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