Metoclopramide hydrochloride monohydrate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80018010
CAS NO.54143-57-6
Purity 98%
MDL NumberMFCD00150634
Molecular FormulaC14H22ClN3O2.HCl.H2O
Molecular Weight354.276
Melting point: 182~188℃
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C14H25Cl2N3O3<br> Molecular weight: 345.28 |
| Physical Properties | Appearance: White to off-white crystalline powder<br> Melting point: 146.5–148°C<br> Solubility: Soluble in water (0.02 g/100 mL at 25°C) |
| Mechanism of Action | Acts as a dopamine receptor antagonist. Enhances gastrointestinal motility and reduces nausea and vomiting by blocking dopamine receptors in the chemoreceptor trigger zone. |
| Therapeutic Uses | Gastrointestinal Disorders: Used to treat gastroparesis, diabetic gastroparesis, and postoperative nausea and vomiting.<br> Other Uses: Also used for gastroesophageal reflux disease (GERD) and functional dyspepsia. |
| Pharmacokinetics | Rapidly absorbed orally, with peak plasma concentrations reached within 1–2 hours. Metabolized in the liver and excreted in urine. |
| Storage Conditions | Store at room temperature, protect from light and moisture. |
| Safety Information | Side Effects: Common side effects include drowsiness, fatigue, and extrapyramidal symptoms.<br> Toxicity: Photosensitive; degrades when exposed to light.<br> Environmental Impact: High mobility in soil, low potential for bioconcentration in aquatic organisms |
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