Methyl(triphenyl)phosphonium chloride
Pharmaceutical Materials 2025-03-02
CAS Number: 1031-15-8 (also seen as 57283-72-4 in some sources)
Molecular Formula: C19H18ClP
Molecular Weight: 312.78 g/mol
Appearance: White powder or crystals
Melting Point: 221°C (dec.)
Usage: It is used as a pharmaceutical intermediate.
| Attribute | Details |
|---|---|
| Chemical Name | Methyl(triphenyl)phosphonium chloride |
| Synonyms | Methyltriphenylphosphonium chloride; Triphenylmethylphosphonium chloride; (Methyltriphenyl)phosphonium chloride |
| CAS Number | 1013-15-8 |
| Molecular Formula | C19H18ClP |
| Molecular Weight | 312.77 g/mol |
| Chemical Structure | A quaternary phosphonium salt consisting of a methyl group attached to a phosphorus atom, with three phenyl groups also attached to the phosphorus atom. The chloride ion serves as the counterion. |
| Appearance | White crystalline solid |
| Melting Point | Above 300°C (decomposition) |
| Solubility | Soluble in organic solvents such as toluene, benzene, and acetonitrile. |
| Physical Properties | Odorless, stable under normal conditions. |
| Chemical Properties | Acts as a reagent in organic synthesis, particularly in Wittig reactions and related phosphorus-based transformations. It is also used as a phase transfer catalyst. |
| Applications | Used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Also employed in research settings for the preparation of complex organic molecules. |
| Safety Information | Handle with caution. Avoid contact with skin and eyes. Wear appropriate personal protective equipment such as gloves, safety glasses, and a lab coat. Store in a cool, dry place away from incompatible materials and oxidizing agents. Follow local regulations for the safe handling and disposal of chemicals. |
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