Methylprednisolone acetate CAS NO.53-36-1

Active Pharmaceutical Ingredients 2025-03-03

Catalog ID80017307

CAS NO.53-36-1

Purity 98%

MDL NumberMFCD00144786 EINEC200-171-3

Molecular formula C24H32O6

Molecular weight 416.5073

Melting point: 228~237°C

Name Methylprednisolone Acetate
Synonyms Mepred
Depo-medrate
depo-medrone
DepMedalone 80
DepMedalone 40
Methylprednisolone Acetate
Methyl prednisolone acetate
Methylprednisolone 21-acetate
6-methyl prednisolone Acetate
6a-Methylprednisolone 21-acetate
METHYLPREDNISOLONEACETATE,MICRONIZED,USP
11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-

Physico-chemical Properties

Molecular Formula C24H32O6
Molar Mass 416.51
Density 1.1156 (rough estimate)
Melting Point 192-195°C
Boling Point 454.82°C (rough estimate)
Specific Rotation(α) D20 +101° (dioxane)
Flash Point 196.5°C
Solubility Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent).
Vapor Presure 5.41E-16mmHg at 25°C
Appearance neat
Color White to Off-White
pKa 12.41±0.70(Predicted)
Storage Condition Refrigerator
Refractive Index 1.4593 (estimate)

​Risk and Safety

Hazard Symbols Xn – Harmful
Risk Codes R63 – Possible risk of harm to the unborn child
R62 – Possible risk of impaired fertility
Safety Description S36/37 – Wear suitable protective clothing and gloves.
S24/25 – Avoid contact with skin and eyes.
HS Code 32041200
Toxicity LD50 oral in rat: > 10gm/kg

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